ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,633, issued on Sept. 30, was assigned to Trustees of Boston University (Boston).
"Inducible dimerization of recombinases" was invented by Wilson W. Wong (Brookline, Mass.) and Benjamin Harris Weinberg (Boston).
According to the abstract* released by the U.S. Patent & Trademark Office: "The technology described herein relates to controlled chemically- or light-induced rejoinder of split-recombinases. In some embodiments, compositions, methods, kits and systems are provided that relate to a split-recombinase system, whereby protein complementation or rejoinder of split-recombinases is mediated by chemical-induced dimerization domains (CIDDs) or light-induced dimerization domains (...