ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,440,545, issued on Oct. 14, was assigned to Trustees of Boston University.
"Methods for treating NETosis and neutrophil activation" was invented by Nelson Ruiz-Opazo (Westwood, Mass.) and Victoria L.M. Herrera (Westwood, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are methods and compositions relating to methods of inhibiting neutrophils, e.g., inhibiting NET release or NETosis, by means of a DEspR inhibitor, e.g., an anti-DEspR antibody reagent. In some embodiments, the methods can relate to the treatment of a disease, e.g., cancer or a disease wherein neutrophils; NETs; or NETosing or NETting neutrophils contribute to pathoge...