ALEXANDRIA, Va., Nov. 18 -- United States Patent no. 12,474,338, issued on Nov. 18, was assigned to Trustees of Boston University (Boston).
"Dynamic tracking of captured targets for enhanced digital biosensing" was invented by Derin Sevenler (Boston) and M. Selim Unlu (Newton Highlands, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Herein is described kinetic assay, in which individual binding events are detected and monitored during sample incubation. This method uses interferometric reflectance imaging to detect thousands of individual binding events across a multiplex solid phase sensor with a large area. A dynamic tracking procedure is used to measure the duration of each event. From this, the tot...