ALEXANDRIA, Va., June 19 -- United States Patent no. 12,329,831, issued on June 17, was assigned to TRANSLATIONAL AND FUNDAMENTAL TECHNOLOGIES INSTITUTE LLC (Encino, Calif.).

"Radionuclide-loaded nanoparticles for focal tissue ablation" was invented by Bashir Akhavan Tafti (Encino, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure features radiopharmaceutical compositions including a radionuclide and an imaging agent encapsulated within, embedded in, or conjugated to a nanoparticle (e.g., via a complexing moiety, such as a chelator), and methods of their use. The radiopharmaceuticals may be formulated for direct administration to the diseased tissue, with minimal or no washout of t...