ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,422, issued on Sept. 9, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).
"Methods for purification of messenger RNA" was invented by Frank DeRosa (Lexington, Mass.), Michael Heartlein (Lexington, Mass.), Jonathan Abysalh (Lexington, Mass.), Daniel Crawford (Lexington, Mass.), Anusha Dias (Lexington, Mass.) and Shrirang Karve (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates, in part, to methods for large-scale purification of mRNA. The method includes, at least, a step of centrifuging an mRNA suspension in a centrifuge comprising a porous substrate at a speed sufficient to remove process contaminants...