ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,305, issued on March 25, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).
"Cationic lipid compounds" was invented by Frank DeRosa (Lexington, Mass.), Shrirang Karve (Lexington, Mass.) and Yi Zhang (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The compounds disclosed herein compound of Formula (I), substructures thereof, and pharmaceutically acceptable salts thereof. The compounds provided herein can be useful for delivery and expression of mRNA and encoded protein, e.g., as a component of liposomal delivery vehicle, and accordingly can be useful for treating various diseases, disorders and conditions, such as those associated...