ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,377,053, issued on Aug. 5, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).
"Cationic polymers" was invented by Frank DeRosa (Waltham, Mass.), Michael Heartlein (Waltham, Mass.), Shrirang Karve (Waltham, Mass.) and Zarna Patel (Waltham, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are cationic polymers comprising monomers such as those described in Formula (I),Such polymers can be useful for the preparation of therapeutic compositions (e.g., compositions comprising nucleic acids such as mRNA). Additionally, therapeutic compositions comprising these cationic, biodegradable polymers can have improved properties and reduced toxicity."...