ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,147, issued on April 22, was assigned to TRANSLATE BIO INC. (Waltham, Mass.).
"PEG lipidoid compounds" was invented by Shrirang Karve (Lexington, Mass.), Yi Zhang (Lexington, Mass.), Frank DeRosa (Lexington, Mass.) and Michael Heartlein (Lexington, Mass.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The compounds disclosed herein (e.g., compounds having a structure according to Formula (I/(II)/(III)/(IV), and (V)) are polymers wherein an organic polymeric segment (e.g., a polyethylene glycol (PEG) group) comprises covalent attachments to two or more lipid substructures, and each lipid substructure independently comprises a hydrophobic moiety and a h...