ALEXANDRIA, Va., June 4 -- United States Patent no. 12,318,489, issued on June 3, was assigned to Translate Bio MA Inc. (Lexington, Mass.).
"Nanoparticle formulations for delivery of nucleic acid complexes" was invented by Fatih Ozsolak (Boston) and Balkrishen Bhat (Carlsbad, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Aspects of the disclosure relate to particle formulations, e.g., nanoparticle formulations, methods of making particle formulations, and methods for delivery of oligonucleotides and/or synthetic RNA, e.g., for increasing gene expression in a targeted manner. In some embodiments, compositions and methods are provided that are useful for posttranscriptionally altering protein and/or RN...