US Patent Issued to Tozaro on Sept. 30 for "Thermally responsive conjugates for DNA polymerase inhibition" (British Inventors)

ALEXANDRIA, Va., Sept. 30 -- United States Patent no. 12,428,677, issued on Sept. 30, was assigned to Tozaro Ltd. (Sharnbrook, Great Britain).

"Thermally responsive conjugates for DNA polymerase inhibition" was invented by Antonio Guerreiro (Cranfield, Great Britain), Francesco Canfarotta (Oadby, Great Britain), Adrian Kinkaid (Saffron Walden, Great Britain) and Alistair Groves (Rushden, Great Britain).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of amplifying a target nucleic acid in a DNA sample comprising (a) contacting the DNA sample containing the target nucleic acid with a DNA polymerase, at least two oligonucleotide primers designed to flank the target nucleic acid, a mixture of dATP, dGTP, ...