ALEXANDRIA, Va., Feb. 19 -- United States Patent no. 12,226,510, issued on Feb. 18, was assigned to Topix Pharmaceuticals Inc. (North Amityville, N.Y.).

"Skin treatment methods and compositions with retinoid and delivery systems thereof" was invented by Burt R. Shaffer (Lloyd Harbor, N.Y.) and Steven M. Hernandez (Blue Point, N.Y.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are stable, non-irritating, retinoid containing formulations and delivery systems for topical application to the skin. The disclosed topical formulations and delivery systems provide controlled release of the retinoid to the skin for the treatment of amenable skin conditions as well as for improvement of aesthetic skin proper...