ALEXANDRIA, Va., July 9 -- United States Patent no. 12,351,838, issued on July 8, was assigned to TOOLGEN Inc. (Seoul, South Korea).
"Target-specific CRISPR mutant" was invented by Joon Sun Lee (Seoul, South Korea), Min Hee Jung (Seoul, South Korea), Yu Ri Choi (Gyeonggi-do, South Korea) and Jeong Joon Lee (Gyeonggi-do, South Korea).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention relates to an artificially engineered CRISPR/Cas9 system. More particularly, the present invention relates to an artificially engineered CRISPR enzyme having enhanced target specificity and a use of an artificially engineered CRISPR/Cas9 system including the same enzyme in genome and/or epigenome manipulation or ...