ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,521,349, issued on Jan. 13, was assigned to TIONLAB THERAPEUTICS (Gyeonggi-Do, South Korea).

"Initial burst release controlled depot composition and a method thereof" was invented by Duck Soo Lim (Suwon-si, South Korea) and Eun Joo Lee (Hwaseong-si, South Korea).

According to the abstract* released by the U.S. Patent & Trademark Office: "A depot composition including a hydrophobic amino acid in a microsphere is provided. The depot composition is capable of controlling the initial burst release of an excess amount of the active ingredient in a formulation including a biodegradable polymer and an active ingredient. The depot composition has excellent suspending ability, and is able to ...