ALEXANDRIA, Va., Oct. 28 -- United States Patent no. 12,447,147, issued on Oct. 21, was assigned to Thomas Jefferson University (Philadelphia).

"Methods of treating, ameliorating, and/or preventing cancer using pyrvinium compositions" was invented by Jonathan R. Brody (Philadelphia) and Christopher William Schultz (Riverton, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described herein are compositions of pyrvinium salts suitable for oral administration. These compositions are in the form of solutions and demonstrate bioavailability both in blood plasma and in pancreatic tissue. Also described herein are methods of treating, ameliorating, and/or preventing pancreatic cancer, including orally administe...