US Patent Issued to Thomas Jefferson University on Aug. 5 for "Fusion proteins that facilitate cancer cell destruction" (Pennsylvania Inventor)

ALEXANDRIA, Va., Aug. 6 -- United States Patent no. 12,378,322, issued on Aug. 5, was assigned to Thomas Jefferson University (Philadelphia).

"Fusion proteins that facilitate cancer cell destruction" was invented by Mark L. Tykocinski (Merion Station, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided is a fusion protein comprising a polypeptide component that blocks binding of CD47 to SIRP alpha and a polypeptide that binds to and triggers a TRAIL receptor or Fas. Also provided is a method of treating cancer in a patient comprising administering the fusion protein of the invention to a patient in need of such treatment."

The patent was filed on April 13, 2022, under Application No. 17/719,894.

*F...