ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,596, issued on March 25, was assigned to Theripion Inc. (Shoreline, Wash.).
"Polynucleotides encoding paraoxonase fusion polypeptides" was invented by Jeffrey A. Ledbetter (Shoreline, Wash.) and Martha S. Hayden-Ledbetter (Shoreline, Wash.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods relating to paraoxonase fusion polypeptides are disclosed. In some aspects, the fusions are bispecific molecules that include a first biologically active polypeptide linked amino-terminal to a biologically active paraoxonase, wherein the first biologically active polypeptide is a DNase, an RNase, a SOD1, a CTLA-4 extracellular domain, a CD40 ...