US Patent Issued to Therakos Development on Sept. 23 for "Method for ex-vivo expansion of regulatory T cells with enhanced suppressive function for clinical application in immune mediated diseases" (Pennsylvania Inventors)

ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,494, issued on Sept. 23, was assigned to Therakos Development Ltd. (Dublin).

"Method for ex-vivo expansion of regulatory T cells with enhanced suppressive function for clinical application in immune mediated diseases" was invented by Tinghua Cao (Malvern, Pa.) and Li Li (Downington, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides methods for the ex-vivo expansion of CD4+CD25+ Tregs. The invention provides a method for producing ex vivo expanded Tregs that may be used to inhibit unwanted human immune responses against self-antigens or allergens. Additionally, the ex vivo expanded Tregs may provide treatment for inflammatory...