US Patent Issued to THE UNIVERSITY OF TOKYO, HANAVAX on April 22 for "Pneumococcal surface proteins" (Japanese Inventors)

ALEXANDRIA, Va., June 6 -- United States Patent no. 12,280,098, issued on April 22, was assigned to THE UNIVERSITY OF TOKYO (Tokyo) and HANAVAX INC. (Tokyo).

"Pneumococcal surface proteins" was invented by Yoshikazu Yuki (Tokyo), Rika Nakahashi (Tokyo) and Hiroshi Kiyono (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides D39-derived mutant PspA that does not undergo deamination and maintains stability as a molecule even around neutral pH range.Specifically, the present invention relates to a protein of the following (a) or (b): (a) a protein comprising the amino acid sequence as set forth in SEQ ID NO: 2 and having pneumococcal vaccine antigenic activity, and a protein subst...