ALEXANDRIA, Va., Oct. 8 -- United States Patent no. 12,435,311, issued on Oct. 7, was assigned to THE UNIVERSITY OF OSAKA (Osaka, Japan).

"Lubricin-localized cartilage-like tissue, method for producing same and composition comprising same for treating articular cartilage damage" was invented by Noriyuki Tsumaki (Kyoto, Japan) and Yoshiaki Takei (Tokyo).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention provides: a lubricin-localized cartilage-like tissue characterized in that, when in an arbitrary cross section passing a first center of mass of a cartilage-like tissue derived from pluripotent stem cells or a center-of-mass region, which is a portion inside a concentric sphere being centered ...