US Patent Issued to THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL on Sept. 9 for "Highly modular biepitopic and bispecific CAR-T cells for cancer immunotherapy" (North Carolina Inventors)

ALEXANDRIA, Va., Sept. 10 -- United States Patent no. 12,410,260, issued on Sept. 9, was assigned to THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL (Chapel Hill, N.C.).

"Highly modular biepitopic and bispecific CAR-T cells for cancer immunotherapy" was invented by Rihe Liu (Chapel Hill, N.C.), Gianpietro Dotti (Chapel Hill, N.C.), JingJing Li (Chapel Hill, N.C.) and Jiyoung Ahn Morrison (Chapel Hill, N.C.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are biepitopic or bispecific chimeric antigen receptors. The chimeric antigen receptors comprise a combination of single domain antibody mimics. The single domain antibody mimics may be monobodies, affibodies, or DARPins. The disclosed chimeric...