US Patent Issued to The University of North Carolina at Chapel Hill on May 27 for "Feedback enabled synthetic genes, target seed match cassettes, and their uses" (Texas Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,311,034, issued on May 27, was assigned to The University of North Carolina at Chapel Hill (Chapel Hill, N.C.).

"Feedback enabled synthetic genes, target seed match cassettes, and their uses" was invented by Steven James Gray (Southlake, Texas) and Sarah Sinnett (Farmers Branch, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "This invention relates to feedback-enabled synthetic genes, polynucleotide target cassettes, vectors, and pharmaceutical compositions for the purpose of providing transgene expression in target tissues that is capable of endogenous regulation for treating disorders such as dose-sensitive intellectual ability disorders, as well...