ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,388, issued on March 25, was assigned to The University of North Carolina at Chapel Hill (Chapel Hill, N.C.).

"Compositions and methods comprising SFRP2 antagonists" was invented by Nancy Demore (Mount Pleasant, S.C.) and Cam Patterson (Little Rock, Ark.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides humanized antibodies and antigen-binding fragments thereof that specifically bind to SFRP2 and compositions comprising such humanized antibodies or antigen-binding fragments thereof. In some aspects, the humanized antibodies or antigen-binding fragments can be used to treat diseases or conditions associated with increase...