US Patent Issued to The University of Chicago on May 27 for "Methods and composition involving thermophilic fibronectin type III (FN3) monobodies" (Illinois Inventors)

ALEXANDRIA, Va., June 17 -- United States Patent no. 12,312,392, issued on May 27, was assigned to The University of Chicago (Chicago).

"Methods and composition involving thermophilic fibronectin type III (FN3) monobodies" was invented by Shohei Koide (Chicago), Shun-Ichi Tanaka (Chicago) and Akiko Koide (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "The current application describes various compositions and methods for the production of FN3-based binding proteins with improved stability properties. Aspects of the disclosure relate to polypeptides comprising a variant fibronectin type III (FN3) domain from Sulfolobus tokodaii or Pyrococcus horikoshii comprising one or more amino acid substitutions o...