ALEXANDRIA, Va., July 23 -- United States Patent no. 12,365,714, issued on July 22, was assigned to The University of Chicago (Chicago).

"Methods and compositions for treating cancer with ECM-affinity peptides linked to cytokines" was invented by Jeffrey A. Hubbell (Chicago), Jun Ishihara (Chicago), Ako Ishihara (Chicago), Koichi Sasaki (Chicago), Melody Swartz (Chicago) and Aslan Mansurov (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "The methods and compositions described herein address the need in the art by providing compositions and methods for a therapy with a cytokine that is specifically targeted to and/or retained intra- or peri-tumorally, limiting systemic exposure and reducing side-effect...