US Patent Issued to The University of Chicago on April 15 for "Chemical probe-dependent evaluation of protein activity and uses thereof" (Illinois Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,276,654, issued on April 15, was assigned to The University of Chicago (Chicago).

"Chemical probe-dependent evaluation of protein activity and uses thereof" was invented by Raymond E. Moellering (Chicago) and Gang Li (Chicago).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed, in part, are methods and compositions for evaluating two or more target proteins from the same family through the use of a molecular construct that contains a targeting group and a retrieval tag. The method can, in some aspects, quantify the activity and function of the proteins of interest, visualize active enzymes at the subcellular and intercellular scale, and increase dyn...