ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,786, issued on April 15, was assigned to The United States of America, as represented by the Secretary, Department of Health and Human Services (Bethesda, Md.).

"Anti-thyroglobulin t cell receptors" was invented by Kenichi Hanada (Bethesda, Md.), Qiong J. Wang (Highland Park, N.J.), James C. Yang (Bethesda, Md.) and Zhiya Yu (Potomac, Md.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed is a synthetic T cell receptor (TCR) having antigenic specificity for an HLA-A2-restricted epitope of thyroglobulin (TG), TG470-478. Related polypeptides and proteins, as well as related nucleic acids, recombinant expression vectors, host cells, and population...