ALEXANDRIA, Va., Dec. 16 -- United States Patent no. 12,497,429, issued on Dec. 16, was assigned to The UAB Research Foundation (Birmingham, Ala.).
"Saponin-based vaccine adjuvants" was invented by Pengfei Wang (Hoover, Ala.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided are variants of saponins that are found in Quillaja saponaria (QS) Molina tree bark that are chemically modified to distinguish them from naturally occurring parent saponins. The modified saponins have increased adjunctive activity compared to the unmodified parent saponins. Defined structures allow for comparisons of the modifying groups with respect to their respective adjunct activity and permit characterized vaccine formulations...