ALEXANDRIA, Va., March 26 -- United States Patent no. 12,258,379, issued on March 25, was assigned to The Trustees of the University of Pennsylvania (Philadelphia).
"Compositions and methods for switchable CAR T cells using surface-bound sortase transpeptidase" was invented by Mauro Castellarin (Ardmore, Pa.) and June Carl (Merion Station, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "The present invention includes compositions and methods comprising sortase immune receptors and sortase chimeric antigen receptors (CARs)."
The patent was filed on Oct. 12, 2019, under Application No. 17/284,407.
*For further information, including images, charts and tables, please visit: http://patft.uspto.gov/netacgi/n...