US Patent Issued to THE TRUSTEES OF PRINCETON UNIVERSITY on Dec. 30 for "In vitro cell-based replacement for the Draize test" (New Jersey Inventor)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,510,534, issued on Dec. 30, was assigned to THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, N.J.).

"In vitro cell-based replacement for the Draize test" was invented by Jeffrey Schwartz (Princeton, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A cell-based device and method are disclosed for in vitro testing of compositions or compounds for irritation potential. Both the device and method comprise a) a confluent layer of corneal epithelial cells supported on a chemically patterned hydrogel, where the cells are aligned with the chemical pattern, b) a collector to receive effluent fluid, and optionally c) a detector. The device and method can also ...