ALEXANDRIA, Va., Aug. 26 -- United States Patent no. 12,398,358, issued on Aug. 26, was assigned to THE TRUSTEES OF PRINCETON UNIVERSITY (Princeton, N.J.).

"Three-dimensional (3D) tissue scaffold with cell alignment" was invented by Stephen B. Bandini (Newton, Mass.), Joshua Spechler (Cherry Hill, N.J.), Craig Arnold (Princeton, N.J.) and Jeffrey Schwartz (Princeton, N.J.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Polymeric substrates, optionally in sheet form, treated with a thin layer of photoresist are perforated by laser ablation. Following removal of the photoresist the polymer substrates perforated with holes are patterned in stripes by photolithography, which is followed by synthesis of a cell-adh...