ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,533,401, issued on Jan. 27, was assigned to THE TRUSTEES OF INDIANA UNIVERSITY (Bloomington, Ind.).
"Devices and methods for modulating ADMA in blood" was invented by Jaipal Singh (Carmel, Ind.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions and methods are provided for metabolically degrading ADMA. In one embodiment a device is provided for reducing a patients ADMA levels in their blood wherein the device comprises a biologically active dimethylarginine dimethylaminohydrolase (DDAH) polypeptide covalently linked to a solid support. In one embodiment a method for reducing ADMA levels in a patients blood comprises the step of contacting the p...