US Patent Issued to THE TRUSTEES OF DARTMOUTH COLLEGE on May 6 for "T-cell receptor-deficient T cell compositions" (New Hampshire Inventor)

ALEXANDRIA, Va., June 10 -- United States Patent no. 12,291,723, issued on May 6, was assigned to THE TRUSTEES OF DARTMOUTH COLLEGE (Hanover, N.H.).

"T-cell receptor-deficient T cell compositions" was invented by Charles L. Sentman (West Lebanon, N.H.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention is directed to modified T cells, methods of making and using isolated, modified T cells, and methods of using these isolated, modified T cells to address diseases and disorders. In one embodiment, this invention broadly relates to TCR-deficient T cells, isolated populations thereof, and compositions comprising the same. In another embodiment of the invention, these TCR-deficient T cells are designed t...