ALEXANDRIA, Va., Sept. 23 -- United States Patent no. 12,421,298, issued on Sept. 23, was assigned to THE SCRIPPS RESEARCH INSTITUTE (La Jolla, Calif.).
"Compositions and methods for evaluating anticoagulant therapeutic efficacy" was invented by Zaverio Ruggeri (La Jolla, Calif.), Wolfram Ruf (San Diego) and Yuichi Kamikubo (San Diego).
According to the abstract* released by the U.S. Patent & Trademark Office: "In various embodiments, disclosed herein are methods of assessing therapeutic efficacy of an anticoagulant. Preferably, the method comprising providing a blood sample; perfusing the blood sample over a surface coated with collagen or immobilized rTF; measuring platelet aggregation and fibrin deposition on the surface coated with co...