US Patent Issued to The Rockefeller University on Oct. 14 for "Anti-HIV antibody 10-1074 variants" (Washington, New York Inventors)

ALEXANDRIA, Va., Oct. 21 -- United States Patent no. 12,441,782, issued on Oct. 14, was assigned to The Rockefeller University (New York).

"Anti-HIV antibody 10-1074 variants" was invented by Michel Nussenzweig (New York), Randal R. Ketchem (Snohomish, Wash.), Christine C. Siska (Seattle), Alison J. Gillespie (Seattle), Rutilio H. Clark (Bainbridge Island, Wash.) and Bruce A Kerwin (Bainbridge Island, Wash.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides optimized broadly-neutralizing anti-HIV antibodies, having modified light chain variable regions and/or heavy chain variable regions leading to improved biophysical characteristics. The present disclosure also provides methods ...