ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,521,442, issued on Jan. 13, was assigned to The Regents of the University of Michigan (Ann Arbor, Mich.).
"ASH1L inhibitors and methods of treatment therewith" was invented by Jolanta Grembecka (Ann Arbor, Mich.), Szymon Klossowski (Ann Arbor, Mich.), Jing Deng (Ann Arbor, Mich.), Tomasz Cierpicki (Ann Arbor, Mich.), Hao Li (Ann Arbor, Mich.), Hongzhi Miao (Ann Arbor, Mich.), Trupta Purohit (Ann Arbor, Mich.) and EunGi Kim (Ann Arbor, Mich.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Provided herein are small molecules that bind to ASH1L and inhibit ASH1L activity, and methods of use thereof for the treatment of disease, including acute leukemia, sol...