US Patent Issued to The Regents of the University of California on March 25 for "Calibration free in-vivo measurement of analytes using electrochemical sensors" (California, Maryland Inventors)

ALEXANDRIA, Va., March 26 -- United States Patent no. 12,257,050, issued on March 25, was assigned to The Regents of the University of California (Oakland, Calif.).

"Calibration free in-vivo measurement of analytes using electrochemical sensors" was invented by Kevin Plaxco (Santa Barbara, Calif.) and Netzahualcoyotl Arroyo Curras (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "Typical electrochemical sensors measure target-induced changes in current output. Such measures of target binding are inconsistent across individual sensors, and furthermore, signal will drift over time when the sensor is deployed for long periods. These shortcomings can be avoided by the novel use of chronoamperometry to me...