ALEXANDRIA, Va., June 25 -- United States Patent no. 12,339,291, issued on June 24, was assigned to The Regents of the University of California (Oakland, Calif.).
"Lipid-DNA labeling of lipid bilayer particles for amplification quantitation" was invented by Thomas Robert Carey (Berkeley, Calif.), Molly Aliza Kozminsky (Berkeley, Calif.) and Lydia L. Sohn (Berkeley, Calif.).
According to the abstract* released by the U.S. Patent & Trademark Office: "Lipid bilayer particles, such as extracellular vesicles (EVs), are labeled with lipid-tagged single-stranded DNA (ssDNA), which is amplified by polymerase chain reaction (PCR) to quantify particles captured via surface marker interactions or complementary oligonucleotide hybridization."
The pa...