US Patent Issued to The Regents of the University of California on July 15 for "Proteolytically cleavable chimeric polypeptides and methods of use thereof" (California Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,358,988, issued on July 15, was assigned to The Regents of the University of California (Oakland, Calif.).

"Proteolytically cleavable chimeric polypeptides and methods of use thereof" was invented by Wendell A. Lim (San Francisco), Kole T. Roybal (San Francisco) and Jasper Z. Williams (San Francisco).

According to the abstract* released by the U.S. Patent & Trademark Office: "The instant disclosure provides chimeric polypeptides which modulate various cellular processes following a cleavage event induced upon binding of a specific binding member of the polypeptide with its binding partner. Methods of using chimeric polypeptides to modulate cellular functions, including e.g., inductio...