US Patent Issued to The Regents of the University of California on Jan. 27 for "Peptide-receptive MHC-I complex compositions and methods" (California Inventor)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,534,510, issued on Jan. 27, was assigned to The Regents of the University of California (Oakland, Calif.).

"Peptide-receptive MHC-I complex compositions and methods" was invented by Nikolaos G. Sgourakis (Philadelphia, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "Compositions that include peptide receptive MHC class I complexes and methods of making and using such complexes are provided. In particular embodiments, such peptide receptive MHC class I complexes are used to form peptide MHC class I (pMHC-I) multimers useful for high throughput applications, such as, for the detection of antigen specific T cells and characterization of T cell profil...