ALEXANDRIA, Va., Jan. 20 -- United States Patent no. 12,527,781, issued on Jan. 20, was assigned to The Regents of the University of California (Oakland, Calif.).

"Treatment of neurodegenerative conditions by disruption of Rhes" was invented by Kenneth Kosik (Santa Barbara, Calif.) and Israel Hernandez (Santa Barbara, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention is directed to the treatment of tauopathic neurodegenerative conditions and the underlying processes thereof. Based on the discovery that Rhes acts as a negative regulator of normal tau clearance, the compositions and methods of the invention may be applied to inhibit Rhes and reduce pathogenic tau aggregation. Rhes may be disr...