US Patent Issued to The Regents of the University of California on Jan. 13 for "Expression-based diagnosis, prognosis and treatment of complex diseases" (California Inventors)

ALEXANDRIA, Va., Jan. 13 -- United States Patent no. 12,522,871, issued on Jan. 13, was assigned to The Regents of the University of California (Oakland, Calif.).

"Expression-based diagnosis, prognosis and treatment of complex diseases" was invented by Nathan Lewis (La Jolla, Calif.), Tiziano Pramparo (La Jolla, Calif.), Eric Courchesne (La Jolla, Calif.) and Vahid Hajihoseini Gazestani (La Jolla, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides for the detection of a perturbed gene network, which includes highly expressed genes during fetal brain development, which is dysregulated in neuron models of autism spectrum disorder (ASD). High-confidence ASD risk genes are upstream regu...