US Patent Issued to The Regents of the University of California on Dec. 9 for "Gene editing of monogenic disorders in human hematopoietic stem cells-correction of X-linked agammaglobulinemia (XLA)" (California Inventors)

ALEXANDRIA, Va., Dec. 9 -- United States Patent no. 12,492,411, issued on Dec. 9, was assigned to The Regents of the University of California (Oakland, Calif.).

"Gene editing of monogenic disorders in human hematopoietic stem cells-correction of X-linked agammaglobulinemia (XLA)" was invented by Donald B. Kohn (Tarzana, Calif.), Caroline Y. Kuo (Beverly Hills, Calif.), David Gray (San Diego), Zulema Romero Garcia (Los Angeles), Roger P. Hollis (Los Angeles) and Anastasia Lomova (Tarzana, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "In certain embodiments methods of treating X-Linked agammaglobulinemia (XLA) in a mammal are provided where the methods comprise: i) providing differentiated T cells and/...