US Patent Issued to The Regents of the University of California on April 15 for "Method to connect chromatin accessibility and transcriptome" (California Inventors)

ALEXANDRIA, Va., June 5 -- United States Patent no. 12,275,936, issued on April 15, was assigned to The Regents of the University of California (Oakland, Calif.).

"Method to connect chromatin accessibility and transcriptome" was invented by Kun Zhang (La Jolla, Calif.) and Song Chen (La Jolla, Calif.).

According to the abstract* released by the U.S. Patent & Trademark Office: "The invention provides scalable methods for measuring chromatin accessibility and RNA expression in the same single cells by connecting chromatin accessibility and transcriptome. Specifically, the disclosure provides a methods for concurrent characterization of gene expression levels and epigenetic landscape within a single cell comprising determining chromatin acce...