US Patent Issued to THE PENN STATE RESEARCH FOUNDATION on Dec. 30 for "Methods and systems for estimating proportion of filled virus capsids using cryo-EM" (Pennsylvania Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,509,663, issued on Dec. 30, was assigned to THE PENN STATE RESEARCH FOUNDATION (University Park, Pa.).

"Methods and systems for estimating proportion of filled virus capsids using cryo-EM" was invented by Suriyasri Subramanian (State College, Pa.) and Susan Lynette Hafenstein (Lemont, Pa.).

According to the abstract* released by the U.S. Patent & Trademark Office: "A method of estimating a proportion of particles filled with material. The method includes: obtaining an image depicting a plurality of particles; generating a plurality of classes based on the plurality of particles; identifying at least one of the plurality of classes having a central portion with a greater density than ...