ALEXANDRIA, Va., April 9 -- United States Patent no. 12,268,677, issued on April 8, was assigned to The Penn State Research Foundation (University Park, Pa.).
"4-aminopyridine (4-AP) and bone morphogenetic protein 2 (BMP-2)" was invented by Sandeep Moothedath Subrahmanian (University Park, Pa.), Prem Kumar Govindappa (University Park, Pa.) and John Elfar (Hummelstown, Pa.).
According to the abstract* released by the U.S. Patent & Trademark Office: "This document relates to methods and materials for using 4-aminopyridine (4-AP) and/or one or more derivatives of 4-AP. For example, a composition containing 4-AP and/or one or more derivatives of 4-AP can be administered (e.g., orally administered) to a mammal to increase a level of bone morph...