US Patent Issued to The Methodist Hospital on Jan. 27 for "Core/shell structure platform for immunotherapy" (Texas Inventor)

ALEXANDRIA, Va., Jan. 28 -- United States Patent no. 12,533,415, issued on Jan. 27, was assigned to The Methodist Hospital (Houston).

"Core/shell structure platform for immunotherapy" was invented by Haifa Shen (Bellaire, Texas).

According to the abstract* released by the U.S. Patent & Trademark Office: "Disclosed are biocompatible core/shell compositions suitable for the delivery of populations of mRNA molecules to mammalian cells. The disclosed core-shell structured multicomponent compositions are optimized for the delivery of mRNAs encoding one or more cancer- or tumor-specific antigens to a population of antigen presenting cells, including, for example, human dendritic cells, macrophages and B cells. Also disclosed are methods for use...