US Patent Issued to THE JOHNS HOPKINS UNVERSITY on July 15 for "Recombinant therapeutic interventions for cancer" (Maryland Inventors)

ALEXANDRIA, Va., July 16 -- United States Patent no. 12,359,209, issued on July 15, was assigned to THE JOHNS HOPKINS UNVERSITY (Baltimore).

"Recombinant therapeutic interventions for cancer" was invented by William R. Bishai (Baltimore), Trinity J. Bivalacqua (Baltimore), Alok Singh (Baltimore), Monali Praharaj (Baltimore) and Takahiro Yoshida (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "Described are methods of suppressing the expression of myeloid-derived suppressor cells (MDSCs), M2 macrophages, and Treg cells in a tumor and inducing the expression of macrophages, dendritic cells (DCs), and T effector cells in a tumor in a subject. A pharmaceutical composition comprising a strain of Mycobact...