US Patent Issued to The Johns Hopkins University, Rapafusyn Pharmaceuticals on Feb. 3 for "Rapafucin derivative compounds and methods of use thereof" (Maryland Inventors)

ALEXANDRIA, Va., Feb. 3 -- United States Patent no. 12,540,144, issued on Feb. 3, was assigned to The Johns Hopkins University (Baltimore) and Rapafusyn Pharmaceuticals Inc. (Baltimore).

"Rapafucin derivative compounds and methods of use thereof" was invented by Jun Liu (Clarksville, Md.), Sam Hong (Baltimore), Brett R. Ullman (Baltimore), Joseph E. Semple (Baltimore), Kana Yamamoto (Baltimore), Puneet Kumar (Baltimore), Magesh Sadagopan (Baltimore) and Jennifer C. Schmitt (Baltimore).

According to the abstract* released by the U.S. Patent & Trademark Office: "The present disclosure provides macrocyclic compounds inspired by the immunophilin ligand family of natural products FK506 and rapamycin. The generation of a Rapafucin library of ma...