ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,508,271, issued on Dec. 30, was assigned to The Johns Hopkins University (Baltimore) and Adarga LLC (Baltimore).

"Prodrugs of 2-PMPA for healthy tissue protection during PSMA-targeted cancer imaging or radiotherapy" was invented by Barbara Slusher (Kingsville, Md.), Michael Nedelcovych (Arlington, Va.), Rana Rais (West Friendship, Md.) and Clemens Kratochwil (Hirschberg, Germany).

According to the abstract* released by the U.S. Patent & Trademark Office: "The use of a class of prodrugs of 2-PMPA that alter tissue distribution of 2-PMPA to non-prostate tissues is disclosed. The presently disclosed prodrugs preferentially distribute to healthy tissues including the kidney, lacrimal gla...