US Patent Issued to The Jackson Laboratory on Dec. 30 for "Method of determining toxicity of an immunomodulatory drug for use in humans" (Maine Inventors)

ALEXANDRIA, Va., Dec. 31 -- United States Patent no. 12,510,548, issued on Dec. 30, was assigned to The Jackson Laboratory (Bar Harbor, Maine).

"Method of determining toxicity of an immunomodulatory drug for use in humans" was invented by James Keck (Bar Harbor, Maine) and Chunting Ye (Bar Harbor, Maine).

According to the abstract* released by the U.S. Patent & Trademark Office: "Humanized mouse models and methods are provided for determining whether administration of an immunomodulatory drug likely elicits a severe cytokine release syndrome in a human. Humanized mouse models and methods are also provided for determining the immunotoxicity in a human of a drug candidate or of drug combinations."

The patent was filed on March 13, 2024, un...